Abstract: This paper mainly introduced the design principle and user interface implementation as well as optimization of quantitative analysis method of software system for domestic first gas measuring instrument which is based on the fast gas chromatography quadrupole mass spectrometer. The WGA1000 software system is a real-time acquisition and control system. It’s based on Windows operating system, MFC programming realization, and its interface style is similar to the Office. The theme framework includes chromatogram control, mass spectrometer control, data acquisition, data playback, component quantitation, alarm and record as well as temperature and pressure control, ion scanning method, peak judgment, peak intensity calculation and concentration correction. So far, the software system has realized that instrument running state and parameters were precisely controlled, the real-time concentration values of each component were obtained by collecting and processing the data quickly, it’s worth noting that the concentration values were received through the software automatically deducting the background density under the condition of the same depth, the accuracy of the results are higher. Then the results were transmitted to the terminal service system, and finally the variation tendency of each component concentration was obtained in the drilling process. By observing and analyzing the change trend of each component concentration, the staff can quickly judge underground strata structure and the content of oil and gas. This work can largely improve the work efficiency and provide a guarantee for drilling safety. We found that in the previous work conventional linear fitting method tends to cause the intercept of fitting equation too big, leading to low signal concentration calculation error, It’s unsuitable for larger linear range data analysis, moreover, conventional ion scanning period is longer and leads to the less number of the points above the peak and the poor peak shape stability. Adopting subsection calibration can avoid the calculation error of the highest point and the lowest point and segmented ion scanning can increase the number of the points above the peak, quantitative results and repeatability of the target components have been significantly improved by optimizing the linear correction method and ion scanning mode. Another major breakthrough about the system is automatic step calculation especially for methane in order to increase the dynamic range. It has been approved after long-term field application and simulation experiments, WGA1000 software system combined with hardware and data analysis software can meet the real-time monitoring requirement of on-line gas measuring instrument in gas logging system.