Abstract: Human liver samples were obtained in autopsy from 16 subjects died suddenly, who were healthy, normal before death and lived in 4 different areas with different dietary types in China. To determine 48 microquantity elements in human liver by inductively coupled plasma mass Spectrometry (ICP-MS),samples were microwave digested using HNO₃ and H₂O₂ .
Rhenium was used as an internal standard element standard. Reference materials of GBW(E) 080193 bovine liver and GBW09101 human hair were analysed by the described method. The analytical values of two standard reference materials showed close agreement with the reference values. The method is simple ,rapid, sensitive and accurate.