液相基体辅助激光解吸/电离质谱法测定紫杉烷类化合物

The Measurement of Taxanes by the Method of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Using Liquid Matrix

摘要: 本文以邻—硝基苯辛醚（NPOE）为液相基体，纤维纸为基底，用基体辅助激光解吸／电离飞行时间质谱法（MALDI－TOF－MS）测定紫杉烷类化合物，研究其激光裂解规律。

Abstract: By using MAI,DI-MS with 2-Nitrophenyl octyl ether (NPOE)as liquid matrix and fibrous paper as substrate, four taxane compounds were measured. The fragmentation of their MALDI mass spectra was discussed.