Determination of Trace Migratory Organo-Tin in Toys by HPLC-ICP-MS

A method for determinating trace migratory organo-tin in toys by high performance liquid chromatography-inductively coupled plasma mass spectrometry (HPLC-ICP-MS) was developed. The organo-tin species dibutyltin(DBT), triphenyltin(TPhT), tributyltin(TBT) and dioctyltin(DOT) were separated on Waters Acquity UPLC HSS T3 analysis column using the mobile phase of V (acetonitrile)∶V (water)∶V (acetic acid)=65∶23∶12，0.1% triethylamine with pH 3.0. This method is quickly and high sensitivity. The detection limits are 0.08, 0.24, 0.14 and 0.65 μg/L for DBT, TPhT, TBT and DOT with injection volume of 50 μL. The recoveries are 80.7%—96.3% and 83.5%—100.4% for the spiked levels of 5 and 50 μg/L, and the RSDs are less than 4.7%, which meet the determination requirements. This method has been used to determine migratory organo-tin in accessible parts of toys, including coating, plastic, wood and textile.