Analysis of Phencynonate by Electron Ionization Mass Spectrometry and Electron Spray Ionization Mass Spectrometry

Electron ionization mass spectrometry (EI-MS) and electron spray ionization mass spectrometry (ESI-MS) were used for the elucidations of the structure and fragmentation pathway of phencynonate (PC). The guasi-molecular ion peak m/z 358M+H⁺, and m/z 156, 342 were detected by ESI-MS, the metabolite of PC in rat urine were also detected and the fragmentation pathway of PC was descripted; m/z 357M⁺ and m/z 138, 175, 154, 215 were detected by EI-MS. Further more, the fragmentation pathway of PC was also explained. The results provided a valuable information for the investigation and development of drugs similar to PC.