Compound Independent Calibration in the ICP-MS Hyphenated Technologies and Its Application Advantages

HPLC-ICP-MS hyphenated techniques were developed for the elemental speciation analysis. Different species of I, Br and Hg were successfully separated and determined. The linier dynamic ranges, the detection limits were discussed. The compound independent calibration (CIC) phenomenon for HPLC-ICP-MS techniques were found and its good potential in applications were discussed as example.