Determination of Pirimicarb, Metalaxyl and Propargite Residues in Fruit and Vegetable by GC-MS/MS

Pirimicarb, metalayl, propargite in fruit and vegetable were determined by gas chromatography-tandem mass spectrometry(GC-MS/MS）. Samples were homogenized, then extracted with acetonitrile. The extracts were concentrated and cleaned up with graphitized carbon black and aminopropyl cartridge. Pesticides were eluted with V（acetonitrile）∶V（ttoluene）=3∶1, and the eluates were concentrated. Quantitation was carried out using matrix-matched standard calibration. The linear range of detection for the method is between 0.002 and 0.5 mg•kg^-1. At the three fortification levels of 0.002, 0.010, 0.050 mg•kg^-1, the average recovery rates are between 91.6% and 110.6% with precision values expressed as relative standard deviation(RSD) lower or equal to 15%, and limits of quantification(LOQs) of three pesticides are all 0.002 mg•kg^-1.