Analysis of Saponins in Ginseng and Red Ginseng by RRLC-Q-TOF-MS

Rapid resolution liquid chromatography coupled with quadrupole-time-of-flight mass spectrometry (RRLC-Q-TOF MS) was developed for analysis the saponins in Ginseng and red Ginseng. The sample was run by RRLC-Q-TOF-MS to identify the peaks. Saponins were identified by comparison with the tR of the standard compounds, the accurate mass, the isotopic ratio pattern, and the characteristic fragment ions obtained from RRLC-ESI-TOF-MS /MS analysis.