Determination of Lead in Blood by Isotope Dilution Multicollector Inductively Coupled Plasma Mass Spectrometry

A method for determination of trace Pb in blood was established by isotope dilution multicollector inductively coupled plasma mass spectrometry (MC-ICP-MS). The average Pb analytical blank obtained in this laboratory is 5.6 ng. A Nist standard reference materials of (SRM) 955b level 1 and (SRM) 955b level 3 were used to evaluate the accuracy of Pb concentration in blood. The measured values are 40.2 and 207.8 μg•L^-1 respecetively, in good agreement with their certified value. The established method was used for determination the Pb concentration of three blood samples, the uncertainty of measurement results were also analyzed and evaluated . The Pb concentration of three blood samples are （102.7±5.5）, （181.7±4.0） and （304.1±3.9） μg•L^-1.