Extractive Electro-spray Ionization Mass Spectrometry for Fast Detection of Salbutamol in Human Urine

A method for rapid determination of salbutamol in human urine was proposed in this study. The effects of the operation parameters, including spray voltage, temperature of the heating capillary, flow rate of extracting solvent, etc. on analysis performance were systematically investigated. Under the optimized experimental conditions, salbutamol in human urine is detected rapidly without any sample preparation with a detection limit lower than 0.1 μg•L^－1.