Surface Desorption Atmospheric Pressure Chemical Ionization Mass Spectrometry for Direct Detection of Ascorbic Acid in Beverages

A novel method was developed for direct detection of ascorbic acid in beverages by surface desorption atmospheric pressure chemical ionization mass spectrometry(SDAPCI-MS) without any sample pretreatment. Using sample needle sampling, the volume of each sampling was less than 5 nL. The average time for a single sample analysis was less than 0.5 min. The limit of detection for ascorbic acid is 1.9×10^-9 g•mL^-1, and the linear range is 10^-8—10^-3 g•mL^-1. The recoveries for four samples spiked with 10^-4 g•mL^-1 ascorbic acid are in the range of 89.9%—109.6%, and the relative standard deviations in the range of 3.2%—5.8%.