Analysis of Blood from Toxic Patient by Gas Chromatography Mass Spectrometry[J]. Journal of Chinese Mass Spectrometry Society, 2005, 26(2): 96-96.
Citation: Analysis of Blood from Toxic Patient by Gas Chromatography Mass Spectrometry[J]. Journal of Chinese Mass Spectrometry Society, 2005, 26(2): 96-96.

Analysis of Blood from Toxic Patient by Gas Chromatography Mass Spectrometry

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  • Received Date: August 27, 2003
  • Revised Date: December 31, 1899
  • The analytical method for identification of the toxicosis in blood was established by gas chromatography mass spectrometry(GC/MS) based on the practical clinical case. 5 mL blood sample of the patient was adjusted to pH4—5 with 10% H 3PO 4, then diluted by 15 mL methanol/acetone (1∶1, v/v ). After supersonic vibration, dehydration with Na 2SO 4, and filtered mixture was concentrated to 1 mL. The extracted sample was comprehensive analyzed and ten toxic components were identified by GC/MS. The main toxic components were furfural, 5 methyl furfural, 5 hydroxymethyl furfural, and 2,3 dihydro 3,5 dihydroxy 6 methyl 4H pyran 4 one, etc. The analytical results provided scientific evidences for salving this kind of patients.
  • [1]
    吴惠勤,张桂英,曾 莉,等.
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