Abstract: In order to create the detection method o methyl alcohol with low detection limit and high precision， kinds of 15 trace elements including Li, Na, K, Ca, Al, Mo, Sb， W in methyl alcohol were determined by inductively coupled plasma-mass spectrometry (ICP-MS). The results show that the linear correlative coefficients are in the range of 0.999 8—1.000. The contents of impurity elements are lower than 0.5 μg/L in methyl alcohol. The results of testing are accurate, the recoveries of the elements are 92%—105%, the relative standard deviation(RSD) is less than 4% and the precision of testing is high. The detection limit of method is low, which is in the range of 0.000 5—0.010 0 μg/L. This method is rapid and accurate， which can determine 15 trace elements in high purity methyl alcohol.