利用直流偏置电压提高矩形离子阱质谱的灵敏度

Application of a DC Offset in a Rectilinear Ion Trap to Improve Sensitivity

  • 摘要: 线性离子阱质谱是近年来被广泛应用的一种性能优良的质谱仪。线性离子阱质量分析器通常是由四根柱状电极合围而成。由于四根电极的几何对称性,在线性离子阱中产生的电场在离子检测方向上也是高度对称的,也就是说,当离子从x方向被逐出离子阱时,将各有50%的离子从+x和-x方向被分别逐出。因此,如果只在线性离子阱的一侧安装离子探测器,则离子的检测效率只有50%。本工作以矩形线性离子阱为研究对象,通过在离子阱中离子逐出方向的一根电极上施加一定的直流偏置电压,利用此直流电压在离子阱中产生的直流电场,使离子阱中存储的离子偏离中心轴分布。这样,离子将在后续离子逐出电场的作用下,被非对称地逐出离子阱。如,可使多数离子从+x方向出射,少数离子从-x方向出射。此时,如果在+x方向安置离子探测器,将获得高于50%的离子探测效率。实验结果表明,直流偏置电压可以明显地提高离子检测效率,例如,在与检测器对侧电极施加正的直流偏置电压时,离子强度在一定电压范围内皆有显著提高。实验所测得的4种不同质荷比的离子提高比例分别是20%、38%、31%、44%。该方法的实验原理简单、实验技术方便易行,可以显著提高线性离子阱检测灵敏度,具有一定的实用价值和应用前景。

     

    Abstract: Linear ion trap (LIT) comprised of four electrodes has been widely used in recent years. Because of the symmetry of the electrodes, the electric field in the LIT is symmetrical in the axial direction. As a result, about 50% of the trapped ions are ejected from one of a pair of electrodes in the process of mass analysis, which can be detected for one detector. In this study, a DC offset was applied to the electrode on the opposite side of the detector, which shifted the positive ions towards the electrode on the side of the detector. This helped the trapped ions to eject unidirectionally. And over 50% of the trapped ions could be detected. Four ions of different mass-to-charge ratios were investigated in this experiment. The results show that the positive DC voltage in a certain range increases the ion intensity. The increments of the ions are 20%,38%,31%,44%, respectively. This method is simple in principle, convenient in experimental technique.

     

/

返回文章
返回