Abstract: Based on the harm of phthalates material to human body health, it is significant to establish a fast method for phthalic acid ester. Taking advantage of extractive electrospray ionization technology, diethyl phthalate (DEP) in 5 different brand of perfume was directly detected by mass spectrometer. The results show that DEP in perfume can be qualitative and quantitative analyzed by extractive electrospray ionization technology, the linear range is 20—1000 μg/L, correlation coefficient is 0.988 9, the limit of detection is 0.39 μg/L, the limit of quantitation is 5.47 μg/L, the recovery is 94.8%—103.4%, the relative standard deviation （RSDs） is 1.5%—4.1%, respectively. The method has low detection limit, high accuracy, fast analysis speed (about 30 s for single sample), the advantages of no complex sample pretreatment, which can provide reference for rapid detection of phthalic acid ester in perfume.