Abstract: Mass Spectrometric Identification and HPLC Separation of Environmental Carcinogen MNU-DNA AdductsLong Yaoting; Lu Miaoqin; Jian Congqiu (Research Center for Eco- Environmental Sciences,Chinese Academy of Sciences, Beijing 100085, China)Abstract:The experimental results of analysis of adducts formed from environmental carcinogenic compound MNU-DNA by combination of HPLC and FABMS are presented in this paper. The analysis of the adducts is carried out after hydrolysis of MNU - DNA adduct. The HPLC efflunts are screened with their UV spectra by DAD and the efflunts of intereste O6 - MG and N7 - MG are collected for MS analysis. The hydrolytical efficiency of DNA and MS fragmental paths of DNA bases adducts are also discussed.Keywords: adduct MNU-DNA, HPLC, MS