Abstract: Based on the data collected by participating in Pesticide Residue Analytical Quality Assurance Study on Food Safety Program organized by WHO, the fitness of gas chromatography mass spectrometry techniques in confirmation process of pesticide residue analysis and its limitation was discussed. Suggestions were given to the application of GC/MS techniques for pesticide residue confirmation under lacking conditions to overcome technical and cost barriers through skilled sample preparation and chromatographic separation using capillary and packed columns.