Abstract: Cr, As, Cd, Nd and Pb in cosmetics were analyzed by ICP-MS, and the sample was disposed by microwave digestion. The matrix suppression effects were corrected in determination with satisfactory results by adding the internal standard elements Ge, In and Bi. Five different kinds of cosmetics were analyzed. In order to check the accuracy of method, Standard Reference Material GBW07603 Bushes, Branches and Leaves were also analyzed. The average recoveries of all elements are 90%-103%, the linear correlation is greater than 0.999, and precision is less than 10%.