Abstract: The developments and performations of surface ionization mass spectrometry of organic compounds are described in this paper. The three modes of ion formation.molecular surface ionization(MSI), dissociative surface ionizat/on(DSI) and associat/ve surface ionization (ASI), the relative sensitivity, the sensitivity comparison of SI and EI, the currents versus sample partial pressure and adsorption time, and the filament temperature are described in detail The surface ionization mass spectrometric analysis of nitrogen-containing aliphatic and cyclic organic compounds) carbohydrate, oxygenic organic compounds, and metalline organic compounds are reviewed. The numbering) molecular weight, (appearance) ionization energy, relative sensitivity) and sensitivity ratio in SI mode to that in EI mode and so on were prcseted in the Table 2.