可的松类药物的GC/MS分析进展

Recent Development on GC/MS Analysis of Corticosteroids

  • 摘要: 可的松类药物在进行GC/MS分析时必须进行化学行生化,本文综述了进行结构改造的各种化学方法,如肟化一硅烷化、烯醇-硅烷化等。

     

    Abstract: Corticosteroids must be derivatised prior to GC/MS analysis. Varieties of derivatization methods are discussed in this paper. It involves methoxyamine-trimethylsilylization(MO-TMS),enol-TMS,encirclization and chemical oxidation.

     

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