电感耦合等离子体质谱法测定成人全血、膳食、尿样和粪便中轻稀土元素及相关性分析

Determination and Correlation Analysis of Light Rare Earth Elements in Human’s Blood, Food,Urine and Feces by ICP-MS

  • 摘要: 为了全面分析人体内稀土元素通过膳食摄取、血液蓄积、尿粪排出之间的关系,应用等离子体质谱法测定成人全血、膳食、尿样及粪便中轻稀土元素含量,比较4个不同膳食类型的城市人体摄取轻稀土元素的差异,并对相同个体的膳食、全血、尿样及粪便中的轻稀土元素进行相关性分析。分别在天津、成都、镇江、太原4个城市采集30名健康成年男性的全血、72 h 膳食、72 h尿样和72 h粪便,膳食、尿样和粪便做冷冻干燥处理后经湿法消解,并采用电感耦合等离子体质谱法测定轻稀土元素含量。4城市采样人体中的稀土含量由高至低依次为粪便、膳食、血液,尿液,但上述样品在4城市人群之间没有显著性差异;同体血、膳食和粪便中轻稀土元素的分布特征符合自然分布特征规律,但尿样中的Sm存在正异常。

     

    Abstract: The light rare earth element(REEs) contents in the blood, food, urine and feces of human bodies were determined by ICP-MS. All the samples were obtained from healthy adult men who lived in the four areas (Chengdu, Taiyuan, Tianjin and Zhenjiang) with different dietary patterns in China. All the individual samples were digested by mixed acid and determined by ICP-MS. Descending order of the light REEs concentrations were in feces, food, blood and urine. There was no significant difference on concentrations of the samples among the four cities. And the distribution pattern of the light REEs in blood, food and feces were similar to that in the nature, while the Sm in the urine was abnormal(REEs).

     

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