气相色谱与高分辨质谱联用(GC-HRMS)检测人尿中低浓度的甾体兴奋剂

The Determination of Doping in Human Urine by GC-HRMS

摘要: 〕本文应用了气相色谱——高分辨质谱（ＧＣ－ＨＲＭＳ）联用及多离子检测技术（ＭＩＤ），建立了人尿中低浓度康力龙、克伦特罗、５β－４羟基甲睾三种甾体激素类药物在低浓度时的检测方法，应用此方法成功地检测了奥林匹克运动委员会（ＴＯＣ）考核尿样中低浓度（２ｎｇ／ｍｌ）的康力龙、克伦特罗、５β－４羟基甲睾等兴奋剂

Abstract: In this paper,GC-HRMS was used to detect doping in human urine.The signal can be obtained at pg sample level by using multiple ion detection.