Abstract: The components of lipophilic part of Ligusticum Chuanxiong Hort. (LCH) were analyzed by use of gas chromatography/mass spectrometer (GC/MS) with NIST library. Under the chromatographic conditions, the samples of LCH from different place with different batch were measured and the common peaks in the fingerprint were confirmed. Twenty two compounds in lipophilic part of LCH were identified and sixteen of them will be used as common peaks of the fingerprint to control the quality of LCH. The fingerprint with active compounds can basically illustrate the composing character of lipophilic part of LCH and the quality of LCH can be controlled by this method.