Abstract: Application of Particle Beam Interface to LC/MSHuang Feng(National Laboratory of Fermentation Technology,Shandong University,Jinan 250100,China)Abstract:Particle Beam Interface(PBI) is one of the techniques designed for liquid chromatography-mass spectrometry(LC/MS). This article discusses the principle of the device and the selection of analysis conditions by introducing some recent published articles and the performance tests of Finnigan MAT SSQ 710 MS-PBI system linked with Waters HPLC pumps.Keywords:particle beam interface; application; LC/MS