Abstract: The Investigation of MALDI-TOFMS of N1GlycosylinosinesAuthor Zhang Jianwei,Min Jimei,Guan Zhu,Zhang Lihe\=(School of Pharmaceutical Sciences,Beijing Medical University,Beijing 100083,China)\=Peng Jiarou,Sun Xulin\=(Medical and Healthy Analytical Center,Beijing Medical University,Beijing 100083,China)\=\=Received 1998-09-17\=\= Abstract \=\;Cyclic adenosine diphosphoribose(cADPR),an important derivative of nucleic acids,is a potent calcium releasing agent postulated to be a new second messenger.By the use of laser desorption/ionization mass spectrometry N1glycosylinosines which are an important intermediate of cyclic adenine diphosphoribose(cADPR)were analyzed with satisfying results.Under laser radiation the fragmentation cause of N1glycosylinosines was discussed.\=\=Key Words:laser desorption/ionization,timeofflight,N1alkylinosines