吲满速尿的GC/MS测定方法及其在尿中代谢的研究

  • 摘要: 本文研究了吲满速尿的GC/MS检测方法,比较了不同的衍生化方法和提取方法,优化了条件,并对吲满速尿的阳性尿的代谢进行探讨,建立了人尿中测定吲满速尿的实用方法。

     

    Abstract: GC/MS Study on Indapamide in Human UrineQin Yang;Wang Xiaobin;Yang Shuming;Zhu Shaotang(National Institute of Sport Medicine,Beijing 100029,China)Received Abstract:A reliable method is described for detection of indapamide in human urine using GC/MS analysis.The derivatization and extraction of indapamide are discussed and an important metabolite of the positive urine is found.The extraction profile of indapamide is investigated by GC/MS.*To whom the respondence should be addressed.Keywords:indapamide,GC/MS,detection,urine,metabolite

     

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