山楂叶总黄酮中α-葡萄糖苷酶抑制剂的超滤质谱筛选研究
Screening and Structures Characterization of α-Glucosidase Inhibitors from Hawthorn Leaves Flavonoids Extract by Ultrafiltration LC-MSn
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Abstract: In vitro α-glycosidase inhibition assays and Ultrafiltration LC-DAD-ESI-MSn were combined to screening α-glucosidase inhibitors from hawthorn leaves flavonoids extract. As a result, hawthorn leaves flavonoids extract showed strong α-glucosidase inhibitory activity, four compounds presented α-glucosidase inhibitory effects were observed and identified by LC-DAD-MSn, and further confirmed by high resolution SORI-CID FT ICR MS data.
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