气相色谱-质谱法测定X胶囊的成分(英文)

Determination of Composition in X Capsule by Gas Chromatography Mass Spectrometry

  • 摘要: 建立了采用气相色谱-质谱法(GC/MS)确定X胶囊中内容物组成的方法。X胶囊中的内容物研磨成细粉后用乙醚提取,挥干乙醚后,溶于四氢呋喃进样。测定结果表明:样品溶液获得的GC/MS谱图数据与甾体化合物甲基睾丸素(甲睾)非常相似。通过对照发现样品的GC/MS谱图与甲睾标准品的GC/MS谱图完全相同。由此可以鉴定X胶囊样品为甲睾。

     

    Abstract: The gas chromatography mass spectrometric technology was applied to analyze the content composition of a healthful X capsule. The contents were ground into powder, extracted by ethyl ether. Then the residue from the extractate was evaporated to dryness, and dissolved in THF to use for gas chromatography mass spectrometric analysis. The experimental results indicated that the component of the capsule was confirmed as methyltestosterone (MT) through comparison with the spectrum obtained from standard MT.

     

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